Endocrine Abstracts

Background: The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D2 receptor binding (Thompson et al., 1997; Pohjalainen et al.,1998). Associations between Taq1A polymorphism DRD2/ANKK1 gene and reward sensitivity including compulsive overeating were reported (Propper et al., 2008; Davis et al., 2008). To study the association of DRD2/ANKK1 Taq1A polymorphism (rs1800497) with obesity we started g...